Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,941 – 2,955 of 5,528 results

2,941

Medchemexpress LLC Deferoxamine (mesylate) | 138-14-7 | 99.8% | 20 MG

Deferoxamine mesylate is an iron chelator that binds to Fe(III) and other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. This compound upregulates HIF-1α levels with good antioxidant activity, shows anti-proliferative activity, and can induce apoptosis and autophagy in cancer cells. It is applicable in studies of diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research.

Binds to Fe(III) and other metal cations
Reduces iron accumulation and deposition in tissues
Upregulates HIF-1α levels
Exhibits good antioxidant activity
Shows anti-proliferative activity
Induces apoptosis and autophagy in cancer cells
Applicable in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research

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2,942

Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.94% | 50 MG

Dihydroergotamine mesylate is a BBB-permeable ergot alkaloid for the research of migraines. It reduces cell survival in A549 and NCI-H226 cells and inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells.

Reduces cell survival in A549 and NCI-H226 cells
Inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells
Induces mitochondrial morphologic alterations and dysfunction
Increases ROS generation and induces apoptosis
Disturbs ATP production in A549 cells
Inhibits STAT3 activation and enhances protein stability of Mcl-1

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2,943

Medchemexpress LLC Almonertinib (mesylate) | 2134096-06-1 | 99.7% | 621.75 | 1 ML

Almonertinib mesylate is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor. It shows high selectivity for EGFR-sensitizing and T790M resistance mutations, with inhibitory activity against T790M, T790M/L858R, and T790M/Del19. It is used for the research of non-small cell lung cancer (NSCLC). This compound can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R, and L861Q.